Abstract
OBJECTIVE: To evaluate the efficacy of anti-adhesion barrier agents following lumbar microdiscectomy. METHODS: Healon GV or Adcon-L was applied to a laminectomy defect overlying the duramater in 60 patients assigned to 3 randomized groups: Group I - Adcon-L (n=21), Group II - Healon GV (n=21), and Group III - control group, no adhesion barrier used (n=18). We conducted this study between 2004 and 2006 at Selcuk University, Konya, Turkey. RESULTS: No significant difference was found between the 3 groups either in the outcome measurements according to visual analogue score and the Oswestry Disability Index or in the radiological evaluation of epidural fibrosis by application of those anti-adhesion barrier agents. When comparing group III with groups I and II, we could not find a statistically significant difference in the clinical results and in the outcome measures (p>0.01). CONCLUSION: The epidural application of popular anti-adhesion barriers, after lumbar microdiscectomy was not found to be effective regarding outcome measures in human spinal surgery.
Article Type
Research Article
First Page
109
Last Page
113
Recommended Citation
Cengiz, Sahika L. and Baysefer, Alper
(2007)
"Efficacy of Adcon-L gel or Healon-GV in epidural fibrosis after lumbar microdiscectomy,"
Neurosciences: Vol. 12:
Iss.
2, Article 3.
DOI: https://doi.org/10.17712/1658-3183.1483