Abstract
Objectives: To define prognostic factors that affect clinical outcome of patients after surgical resection of spinal intramedullary ependymoma.
Methods: A retrospective multi-center study, including all cases operated on from 2007 through 2024 at 3 institutes. Data on surgical factors included: resection extent, intraoperative neurophysiology monitoring methods, and intraoperative/postoperative complications.
Results: A total of 19 patients were included with a mean age of 37.8 years (SD = 13.2, range 8–57 years). The majority of ependymomas (n = 14, 73.7%) were in the cervical region. The most common presenting symptoms included pain in 14 patients (73.7%), sensory deficits in 11 patients (57.8%), and motor deficits 10 patients (52.6%). As per preoperative McCormick grading, 31.6%, 10.5%, and 31.6% were grade I, II, and III, respectively. Postoperatively, 57.9% of patients improved to McCormick grade I. Total gross tumor resection was achieved in 15 participants (78.9%). Syndromes, specifically neurofibromatosis type II, were significantly associated with a chance of recurrence (p = 0.004) and the need for a second surgery (p = 0.018).
Conclusion: The preoperative neurological status correlates significantly with the postoperative outcome of the patient.
Article Type
Original Study
First Page
34
Last Page
40
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Recommended Citation
Albuhairan, Reem; Alqahtani, Laila; Sayed, Ahmed Gamal; Alkhaibary, Ali; Khairy, Sami; Farash, Faisal; Alassiri, Ali H.; and Alkhani, Ahmed
(2026)
"Predictors of Long-Term Outcome and Recurrence of Intramedullary Spinal Ependymomas: A multicenter study,"
Neurosciences: Vol. 31:
Iss.
1, Article 5.
DOI: https://doi.org/10.17712/1658-3183.1004