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Abstract

OBJECTIVE: To assess the neurological complications of Behcet’s disease among Jordanian patients, and to relate these complications with the presence of antiphospholipid antibodies. METHODS: Twenty-two patients with Neuro-Behcet’s disease admitted to King Hussein Medical Center, Amman, Jordan between January 1997 and August 1999, were evaluated clinically and by neuroimaging techniques. There were 17 males (77%), 5 females (23%), with a mean age of 36 years (range 18-51). Antiphospholipid antibodies were tested in all the patients. RESULTS: Brain infarcts were seen in 18 cases; 12 in the anterior fossa, 6 in the posterior fossa, and 2 patients had spinal cord ischemia. Five patients had sinus thrombosis; 4 in the superior sagittal sinus, one in the sigmoid sinus, all were proved by magnetic resonance venogram. All patients were tested for antiphospholipid antibodies and showed negative results. CONCLUSION: Brain infarcts are the most common neurological complications of Behcet’s disease, less common is sinus thrombosis, and we found no link between these complications and the presence of antiphosphplipid antibodies.

Article Type

Research Article

First Page

224

Last Page

226

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